Kerman University of Medical Sciences International Journal of Health Policy and Management 2322-5939 10 Special Issue on WHO-CHOICE Update 2021 11 01 Cost-Effectiveness of Population Level and Individual Level Interventions to Combat Non-communicable Disease in Eastern Sub-Saharan Africa and South East Asia: A WHO-CHOICE Analysis 724 733 4056 10.34172/ijhpm.2021.37 EN Melanie Y. Bertram Department of Health Systems Governance and Financing, World Health Organization, Geneva, Switzerland 0000-0002-7641-8943 Daniel Chisholm Department of Mental Health and Substance Abuse, World Health Organization, Geneva, Switzerland 0000-0002-4114-0961 Rory Watts Department of Health Systems Governance and Financing, World Health Organization, Geneva, Switzerland 0000-0003-4904-2626 Temo Waqanivalu Department of Prevention of Non-Communicable Diseases, World Health Organization, Geneva, Switzerland 0000-0003-3946-4913 Vinayak Prasad Department of Prevention of Non-Communicable Diseases, World Health Organization, Geneva, Switzerland 0000-0001-6961-739X Cherian Varghese Department of Management of Non Communicable Diseases, Violence and Injury, World Health Organization, Geneva, Switzerland 0000-0001-6907-0451 Journal Article 2020 01 30 <span class="fontstyle0">Background  </span><br /><span class="fontstyle2">To determine the health system costs and health-related benefits of interventions for the prevention and control of non-communicable diseases (NCDs), including mental health disorders, for the purpose of identifying the most cost-effective intervention options in support of global normative guidance on the best-buy interventions for NCDs. In addition, tools are developed to allow country contextualisation of the analyses to support local priority setting exercises.</span><br /> <br /><span class="fontstyle0">Methods  </span><br /><span class="fontstyle2">This analysis follows the standard WHO-CHOICE (World Health Organization-Choosing Interventions that are Cost-Effective) approach to generalized cost-effectiveness analysis applied to two regions, Eastern sub-Saharan Africa and South-East Asia. The scope of the analysis is all NCD and mental health interventions included in WHO guidelines or guidance documents for which the health impact of the intervention is able to be identified and attributed. Costs are measured in 2010 international dollars, and benefits modelled beginning in 2010, both for a period of 100 years.</span><br /> <span class="fontstyle2"><br /></span><span class="fontstyle0">Results  </span><br /><span class="fontstyle2">There are many interventions for NCD prevention and management that are highly cost-effective, generating one year of healthy life for less than Int. $100. These interventions include tobacco and alcohol control policies such as taxation, voluntary and legislative actions to reduce sodium intake, mass media campaigns for reducing physical activity, and treatment options for cardiovascular disease (CVD), cervical cancer and epilepsy. In addition a number of interventions fall just outside this range, including breast cancer, depression and chronic lung disease treatment.</span><br /> <br /><span class="fontstyle0">Conclusion  </span><br /><span class="fontstyle2">Interventions that represent good value for money, are technically feasible and are delivered for a low per-capita cost, are available to address the rapid rise in NCDs in low- and middle-income countries. This paper also describes a tool to support countries in developing NCD action plans.</span> https://www.ijhpm.com/article_4056_9529fbba677729d3206b3b9073d1e9ca.pdf